Txij li thaum xyoo 2007, peb yog ib qho ntawm cov thawj cojorlistat hmoovmanufacturers tus neeg muag khoom nyob rau hauv Suav teb
Orlistat (CAS NO.96829-58-2) yog ib qho tshuaj tsim los kho kev rog rog.Nws yog tsuas yog siv los tiv thaiv kev nqus ntawm cov rog los ntawm tib neeg kev noj haus, yog li txo qis caloric kom tsawg.Tsis tas li ntawd, nws yog npaj rau kev siv ua ke nrog tus kws kho mob saib xyuas kev noj zaub mov kom tsawg.
| Yam khoom | Kev xav tau | Cov qhabnias xeem |
| Qhov tshwm sim | thaum lub sij hawm off-thaum hmoov | Dawb hmoov |
| Kev txheeb xyuas | HPLC tuav lub sijhawm | Ua raws |
| Melting Point | 42 ºC -45 ºC | 42 ° C-44 ° C |
| Kev sib hloov kho qhov muag tshwj xeeb | -31.0° ~ 41.0° | -36.0 ° |
| Purity los ntawm HPLC | tsis pub tsawg tshaj 98.0% | 98.5% |
| Tag nrho impurity | tsis ntau tshaj 2.0% | 1.6% |
| Max tus kheej impurity | tsis ntau tshaj 0.5% | 0.3% |
| Cov ntsiab lus dej% (K&F) | tsis ntau tshaj 0.5% | 0.1% |
| Cov kuab tshuaj residual | EtOH tsis ntau tshaj 0.5% | ND |
| EtAC tsis ntau tshaj 0.5% | ND | |
| n-Heptane tsis ntau tshaj 0.5% | tsawg dua 0.1% | |
| Residue ntawm ignition | tsawg dua 0.2% | 0.10% |
| Heavy hlau li Pb | tsis ntau tshaj 20 ppm | tsawg dua 20 ppm |
| Kev ntsuam xyuas (HPLC) | tsis pub tsawg tshaj 98.0% | 99.60% |
| Xaus | Ua tau raws li Cov Kev Xav Tau | |
Orlistat yog ib qho kev lees paub thoob ntiaj teb daim ntawv tshiab ntawm cov tshuaj poob phaus.Nws lub npe lag luam yog Sainike thiab thawj zaug tau muag hauv New Zealand hauv xyoo 1998. Orlistat yog lub sijhawm ntev thiab muaj txiaj ntsig zoo tshwj xeeb hauv plab hnyuv lipase inhibitor, thiab nws yog insoluble hauv dej, soluble hauv chloroform, thiab yooj yim soluble hauv ethanol.
Orlistat tuaj yeem siv kho mob los kho kev rog.Feem ntau, koob tshuaj 120mg yog noj peb zaug hauv ib hnub hauv ib teev ntawm pluas noj.Kev poob phaus pib tshwm sim tom qab ob lub lis piam ntawm kev siv.Nws tuaj yeem siv tsis tu ncua rau 6-12 lub hlis, thiab nws cov teebmeem yuav tsum tsis txhob nce ntxiv tom qab noj txhua hnub ntau dua 400mg.Cov tshuaj no yog tsim los siv ua ke nrog kev noj zaub mov uas tsis muaj calorie ntau los ntawm cov neeg rog thiab rog, thiab nws kuj tseem siv tau los ua kev kho mob ntev rau cov neeg mob uas tau ntsib qhov hnyav hnyav.Orlistat muaj kev tswj qhov hnyav mus ntev uas txo thiab tswj qhov hnyav thiab tiv thaiv kev rov qab los.Kev siv Orlistat tuaj yeem txo qhov tshwm sim ntawm qhov hnyav hnyav thiab cov kab mob, suav nrog hypercholesterolemia, ntshav qab zib hom 2, tsis muaj qabzib siab ntev, hyperinsulinemia, thiab kub siab, thiab nws tuaj yeem txo cov roj cov ntsiab lus hauv nruab nrog cev.Orlistat kuj kho cov ntshav lipid: nws tuaj yeem txo cov ntshav triglycerides (TG) thiab qis lipoprotein cholesterol (LDL-C), thiab nws tuaj yeem nce qhov sib piv ntawm cov lipoproteins ntau ntom rau cov lipoproteins tsawg ntom hauv cov neeg mob rog.
Hebei Guanlang Biotechnology Co., Ltd. belongs rau Guanlang Group, uas tau tsim nyob rau hauv 2007, nyob rau hauv Shijiazhuang nroog uas yog lub peev ntawm Hebei xeev thiab hub sector ntawm Beijing Tianjin thiab Hebei thiab muaj kom zoo dua ntawm kev thauj mus los yooj yim.Peb lub tuam txhab yog niaj hnub high-tech chemical enterprise nrog Kev Tshawb Fawb & Kev Tsim Kho, ntau lawm thiab muag.Peb muaj peb tus kheej lub Hoobkas thiab chaw kuaj mob, kuj muab kev pabcuam customized synthesis rau peb cov neeg siv khoom.
